Breast cancer is the most common cancer in women. 5-10% of breast cancers can be linked to gene mutations inherited from either parent. The most common genes mutated in inherited breast cancer are BRCA1 and BRAC2. However, 85% of breast cancers are the result of sporadic mutations in 29 other genes. Next Generation Sequencing makes it possible to test all 31 genes across the entire exonic regions. Mutations in these genes provide important information regarding tumor development, tumor progression, and can be used as a reliable predictor of personalized cancer therapies. We have developed a Breast Cancer Therapy Panel that includes the 31 genes associated with breast cancer and 38 genes that are related to drug sensitivity and efficacy. This panel is designed to help doctors diagnose and provide treatment options for breast cancer patients and those at risk for breast cancer.